Bioinformatics Tools @ NBBNet: Online Infrastructure for the Management and Analysis of Biological Data
MOHD FIRDAUS RAIH, MOHD YUNUS SHARUM, AHMAD FUAD HILMI
MUHAMMAD, HAFIZA AIDA AHMAD, RAJA MURZAFERI RAJA MOKTAR,
MOHD NOOR MAT ISA, NOR MUHAMMAD MAHADI & RAHMAH MOHAMED
ABSTRACT
The use of informatics tools for the management and analysis of sequences for nucleic acids and proteins has resulted better throughout capability of wet lab research work to infer biological data to functional biological information. The field of computational biological information management and analysis is generally known as bioinformatics. We discuss some tools and processes which have been developed or integrated into a data management and information presentation pipeline by the Malaysian National
Biotechnology and Bioinformatics Network. Central to this is the Bioinformatics Tools @ NBBnet online infrastructure system. This infrastructure system utilizes grid computing technology. In addition, the deployment of niche databases and database shells for research applying specific datasets
such as a particular protein function, protein family or genomes have been
discussed.
Keywords: Bioinformatics; meta-server; niche datasets; web infrastructure; grid computing
ABSTRAK
Penggunaan teknologi maklumat dalam pengurusan dan analisis bagi jujukanjujukan asid nukleik dan protein telah mengakibatkan peningkatan keupayaan penterjemahan data yang dijana di makmal kepada maklumat biologi yang berguna. Bidang pengurusan dan analisis maklumat biologi berkomputer
juga dikenali sebagai bioinformatik. Penerbitan ini membincangkan beberapa perisian dan proses yang telah disepadukan dalam satu aliran kerja bagi analisis dan pemaparan data serta maklumat biologi oleh Rangkaian Bioteknologi dan Bioinformatik Kebangsaan Malaysia (NBBnet). Prasarana dalam talian ini berpusat sekeliling sistem Bioinformatics Tools @ NBBnet. Sistem prasarana ini mengaplikasikan teknologi pengkomputeran grid. Di samping itu, beberapa konsep pengurusan dan analisis data subset daripada famili protein tertentu juga dibincangkan.
Kata Kunci: Bioinformatik; meta-server; data set khusus; prasarana web; pengkomputeran grid
