Sains
Malaysiana 49(1)(2020): 129-132
http://dx.doi.org/10.17576/jsm-2020-4901-15
Essential Hypertension Onset in a 12-Year-Old
Adolescent
(Permulaan Tekanan Darah Tinggi pada Remaja 12 Tahun)
MOHD SHAIFUL EHSAN SHALIHIN1*, ZULKIFLI HARUN2
& ISKANDAR FIRZADA OSMAN2
1Department of Family Medicine, Kulliyyah
of Medicine, International Islamic University of Malaysia, IIUM Kuantan Campus,
Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang Darul Makmur, Malaysia
2Klinik Kesihatan Jaya Gading, Jaya Gading,
25150 Kuantan, Pahang Darul Makmur, Malaysia
Received: 20 August 2019/Accepted: 17 October 2019
ABSTRACT
Essential
hypertension in adolescents is increasing in trend worldwide in view of
increasing prevalence of childhood obesity and sedentary lifestyle. Generally,
secondary hypertension is suspected if it occurs at pre-pubertal age or
presented with resistant hypertension. We reported a case of 12-year-old
adolescent male diagnosed with essential hypertension during opportunistic
screening with suboptimal blood pressure control at primary care. Poor response
of his blood pressure control despite his compliance to medications had cause
him emotional distress. We referred this child for assessment of secondary
hypertension but it turned out to be negative. Surprisingly, his blood pressure
responded well with prazosin and diltiazem combination during adjustment period
prior to renovascular assessment. His hypertension is well controlled till now.
This case proved that essential hypertension is still possible in early
non-morbid obese adolescent despite negative family history of hypertension.
Individualised treatment should be adapted rather than questioning the
compliance of the adolescent.
Keywords: Adolescent; diltiazem; hypertension; prazosin
ABSTRAK
Kes tekanan darah tinggi dalam kalangan
remaja semakin meningkat oleh kerana peningkatan kes kegemukan dan pengamalan
gaya hidup yang tidak sihat sejak daripada usia kanak-kanak. Secara umumnya,
tekanan darah akibat punca kesihatan yang lain perlulah dikenal pasti terutama
jika tekanan darah tinggi terjadi pada usia sebelum akil baligh atau pada
keadaan tekanan darah yang sukar untuk dikawal. Kami sertakan laporan kes berkaitan remaja lelaki berusia 12 tahun yang
telah dikenal pasti mengalami tekanan darah tinggi yang sukar untuk dikawal
secara optimum di klinik kesihatan. Kawalan tekanan darah yang tidak berkesan
biarpun telah mematuhi pengambilan ubat yang disyorkan telah mengakibatkan
tekanan emosi kepada remaja ini. Justeru kami telah merujuk remaja ini kepada
pihak hospital namun rawatan susulan mendapati remaja ini tidak mempunyai
masalah lain berkaitan darah tinggi beliau. Tanpa dijangka, bacaan tekanan
darahnya menjadi terkawal dengan pengambilan ubat prazosin dan diltiazem
sebelum menjalani penilaian fungsi saluran darah buah pinggang. Ternyata
tekanan darahnya menjadi terkawal sehingga sekarang. Kes ini berjaya
membuktikan tekanan darah tinggi boleh terjadi pada usia awal remaja yang tiada
masalah obesiti mahupun tiada sejarah darah tinggi keturunan. Pencarian ubat
darah tinggi yang sesuai untuk kawalan darah tinggi dalam kalangan remaja
perlulah menjadi keutamaan berbanding mempertikaikan kejujuran remaja dalam
mengambil ubat seperti yang telah ditetapkan.
Kata kunci: Darah tinggi; diltiazem; prazosin; remaja
REFERENCES
Anyaegbu, E. & Dharnidharka, V.
2014. Hypertension in teenager. Pediatric
Clinics of North America 61(1): 131-151.
Bell, C.S., Samuel, J.P. &
Samuels, J.A. 2019. Prevalence of hypertension in children applying the New
American Academy of pediatrics clinical practice guideline. Hypertension 73(1): 148-152.
Compas, B.E., Jaser, S.S., Dunn, M.J. & Rodriguez,
E.M. 2012. Coping with chronic illness in childhood and adolescence. Annual Review of Clinical Psychology 8(1):
455-480. doi: 10.1146/annurev-clinpsy-032511-143108.
Eden, H.J.K., Edmondson, C.L., Hill,
J. & Tim, O.B. 2011. Treatment non-adherence in teenage and young adult
patients with cancer. The Lancet Oncology 12(1): 100-108.
Flynn, J.T., Kaelber, D.C.,
Baker-Smith, C.M., Blowey, D., Carroll, A.E., Daniels, S.R., de Ferranti, S.D.,
Dionne, J.M., Falkner, B., Flinn, S.K., Gidding, S.S., Goodwin, C., Leu, M.G.,
Powers, M.E., Rea, C., Samuels, J., Simasek, M., Thaker, V.V. & Urbina,
E.M. 2017. Clinical practice guideline for screening and management of high
blood pressure in children and adolescents. American
Academy of Paediatrics 140(3): e20171904.
Jiang, S-Z., Lu, W., Zong, X-F., Ruan, H-Y. & Liu, Y.
2016. Obesity and hypertension. Experimental
and Therapeutic Medicine 12(4): 2395-2399.
Matoo, T.K. 2019a.
Definition and diagnosis of hypertension in children and adolescents. Accessed by https://www.uptodate.com/contents/definition-and-diagnosis-of-hypertension-in-children-and-adolescents#!.
Mattoo, T.K. 2019b. Evaluation of
hypertension in children and adolescents. Accessed
by https://www.uptodate.com/contents/evaluation-of-hypertension-in-children-and-adolescents#!.
Messerli, G.R., Kamath, G. &
Franz, H. 2010. Should alpha-blockers even be used as antihypertensive drugs? Clevelan Clinic Journal of Medicine 12(884):
887-888.
Neutze, D.M. & Viera,
A.J. 2010. Diagnosis of secondary hypertension: An age-based approach. American Family Physician 82(12):
1471-1478.
Raj, M. & Kumar, R.K. 2010. Obesity in children and
adolescents. The Indian Journal of
Medical Research 132(5): 598-607.
Rao, G. 2016.
Diagnosis, epidemiology, and management of hypertension in children. Pediatrics 138(2): e20153616.
Rodriguez-Cruz, E. 2017. Pediatric hypertension treatment
& management. Medscape. https://emedicine.medscape.com/article/889877-treatment.
Santos, T., de Matos, M.G., Marques, A., Simões, C.,
Isabel, L. & Machado, M.d.C. 2016. Adolescent's subjective perceptions
of chronic disease and related psychosocial factors: Highlights
from an outpatient context study. BMC
Pediatrics 16(1): 211. doi: 10.1186/s12887-016-0748-x.
Schmidt, R.J.
& Akbar, S.R. 2018. Renovascular hypertension medication. Medscape. Accessed by
https://emedicine.medscape.com/article/245140-medication.
Tahir Aris, Muhammad
Fadhli Mohd Yusoff, Abdul Aiman Abd Ghani, Noor Ani Ahmad, Mohd Azahadi Omar,
Tee Guat Hiong, Nur Hazwani Mohd Hasri, Nur Fadzilla Mohd Radzi, Nur Syazwani
Manan & Nurul Aini Kamaruddin. 2015. Non-Communicable
Diseases, Risk Factors & Other Health Problems. National Health
Morbidity Survey 2015. Volume II. Ministry of
Health Malaysia.
*Corresponding
author; email: shaifulehsan@iium.edu.my
|