Fakulti Farmasi | Faculty of Pharmacy, UKM
Centre for Quality
Management of Medicines
Clinical Pharmacy Practice
CURRENT ACTIVE PROJECTS:
A/ Prof Noraida Mohamed Shah
Re-strategizing Chemotherapy Induced Nausea and Vomiting (CINV) prophylaxis in Malaysia
- In this research, we planned to conduct a clinical trial on CINV prophylaxis together with interview of patients and healthcare professionals caring for cancer patients to explore their perspectives and experiences related to CINV. Findings from this research may reshape the clinical practice on CINV prophylaxis in Malaysia.
Dr Adliah Mhd Ali
Exploring issues and developing patient-centered counselling tool for dispensing hormonal contraceptives in community pharmacy settings
- Unintended pregnancy is a major global issue. The incidence of induced abortion is high, although the practice of contraception at the community remains an important issues to be addressed in Malaysia. Various studies published focusing on knowledge, awareness and perception of contraception, however lacking in patient centered counselling tools. This study will develop the tools to guide community pharmacists in dispensing contraception in Malaysia.
Factors contributing to medication wastage among patients receiving subsidized medications and pharmacist intervention program
- In Malaysia, the major provider of healthcare services, the public health care system, is heavily subsidized by the government. However, previous studies reported patients adhering to their medications varies. Identifying the high risk group of patients likely to waste their subsidized medications accurately due to non-adherence and other related factors is important to conduct appropriate early intervention.
Dr Chong Wei Wen
Antimicrobial resistance and stewardship: General public and health providers’ perspectives.
- Antimicrobial resistance (AMR) has become a significant global threat to human health worldwide. Multiple perspectives from the general public and health providers are important to understand the causes and key drivers of AMR. This research aims to study the perspective and awareness of the Malaysian general public related to antimicrobial use and AMR, physicians’ decision-making process when prescribing antimicrobials, and the roles of pharmacists in the implementation of antimicrobial stewardship strategies. Outcomes from this research may assist in identifying targets for quality improvement in current approaches to combat AMR.
Dr Nurul Ain Mohd Tahir
Lean six sigma methodologies for novel identification, characterisation and evaluating the impact of drug related problems among thalassemia patients.
- Several studies had been done to investigate DRPs in various other diseases but the results are less applicable to thalassemia because of the rarity and complexity of the disease and treatment characteristics. Undetected or untreated DRPs may cause significant morbidity and mortality, as well as a substantial economic burden due to increased healthcare resource utilization; therefore careful assessment of DRPs in the thalassemia population is crucial. The objective of the study is to investigate the DRPs and the associated factors among patients with thalassemia, and the impact of DRPs on the clinical and economic outcomes. This study applied the characterization phase of the DMAIC approach which includes the process of defining, measuring and analyzing problems related to medication errors. The findings from this research seek to provide baseline information on the pattern and prevalence of DRPs, factors related to the occurrence of DRPs, their clinical and economic impact in this patient population, so as to enable optimization of current management by identifying and preventing DRPs and also to serve as preliminary data for future research.
Dr Siti Azdiah Abdul Aziz
Health domains characterizing frailty in Asian people living with HIV receiving antiretroviral therapy
- Non-infectious, old-age diseases such as cardiovascular diseases, malignancies, cognitive decline, and geriatric syndromes are increasingly prevalent at chronologically younger PLWH receiving combination ART compared to uninfected individuals. A total of 90% of PLWH aged 50 and older (mean age, 59 years) have at least one chronic, non-HIV related comorbidity. Research on frailty among Asians with HIV has only recently been explored and is still lacking. Thus, further investigation is needed, particularly in our setting where HIV treatment is often initiated during advanced stages of the disease. Thus, the study aimed to compare health domains characterizing frailty determined by multiple frailty instruments between frail PLWH and frail matched controls; identify associated risk factors and the impact of frailty on negative health outcomes in predominantly young PLWH receiving ART. Findings from this study suggest the need to review current interventional approaches to optimize management of PLWH
Dr Chandini Menon Premakumar
Knowledge and Attitude of Healthcare Professionals to Total Parenteral Nutrition in Neonatal Intensive Care Units
- Total parenteral nutrition (TPN) is widely used as a nutrition support therapy in the neonatal intensive care units for very preterm neonates. There probably exists a wide variation in practice among healthcare professionals handling TPN in different hospital settings within Malaysia. The purpose of this study is to evaluate the awareness amongst healthcare professionals to total parenteral nutrition in neonatal intensive care units. The outcome from this research may aid in improving the professional role and better integration of providing good quality and safe TPN in the neonatal population in Malaysia.
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