Sains Malaysiana 41(1)(2012): 47–52

Alkaloid Constituents of Haplophyllum Laeviusculum (Rutaceae)

(Kandungan Alkaloid daripada Haplophyllum laeviusculum (Rutaceae))

Parimah Parhoodeh, Mawardi Rahmani*, Najihah Mohd Hashim Mohd. Aspollah Sukari

& Gwendoline Cheng Lian Ee

Chemistry Department, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia

Received: 25 April 2011 / Accepted: 29 June 2011

ABSTRACT

The investigation of the aerial parts of Haplophyllum laeviusculum (Rutaceae), a perennial herb native to Iran, afforded three alkaloids, skimmianine (1), lunamarine (2), ribalinidine (3) and and two common sterols, γ-sitosterol and campesterol. The structures of compounds were identified by using spectroscopic methods by using UV, IR, NMR, MS spectra and also by comparison with previous works. There has been no detail phytochemical investigation report on the plant carried previously. This is the first report on the identification of skimmianine (1), lunamarine (2) from genus Haplophyllum.

Keywords: Haplophyllum laeviusculum; lunamarine; ribalinidine; skimmianine

ABSTRAK

Kajian terhadap bahagian atas Haplophyllum laeviusculum (Rutaceae), tumbuhan herba yang berasal dari Iran, telah menghasilkan tiga alkaloid, skimmianina (1), lunamarina (2), ribalinidina (3) dan dua sterol umum, γ-sitosterol and kampesterol. Struktur bagi sebatian ini telah dikenalpasti dengan menggunakan kaedah spektroskopi UV, IM, NMR dan SJ dan juga perbandingan dengan laporan kajian sebelum ini. Tiada kajian fitokimia terperinci telah dilakukan sebelum ini ke atas tumbuhan H. laeviusculum. Ini adalah laporan pertama kehadiran skimmianina (1), lunamarina (2) daripada tumbuhan genus Haplophyllum.

Kata kunci: Haplophyllum laeviusculum; lunamarina; ribalinidina; skimmianina

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*Corresponding author; email: mawardi@science.upm.edu.my