Sains Malaysiana 38(4)(2009): 473–481 

Status Selenium Serum Populasi di Daerah Hulu Langat, Selangor, Malaysia

(Serum Selenium Status Among Populations in Hulu Langat District, Selangor, Malaysia)

Ismarulyusda Ishak* & Jamaludin Mohamed

Jabatan Sains Bioperubatan, Fakulti Sains Kesihatan Bersekutu

Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz

50300 Kuala Lumpur, Malaysia

Khairul Osman

Program Sains Forensik, Fakulti Sains Kesihatan Bersekutu

Universiti Kebangsaan Jalan Raja Muda Abdul Aziz

50300 Kuala Lumpur, Malaysia

Zaleha Md Isa

Jabatan Kesihatan Masyarakat, Fakulti Perubatan

Universiti Kebangsaan Malaysia, Kuala Lumpur

56000 Cheras, Malaysia

Zakiah Ismail

Pusat Penyelidikan Perubatan Herbal

Institut Penyelidikan Perubatan, Jalan Raja Muda Abdul Aziz

50300 Kuala Lumpur, Malaysia

Mohd Fairulnizal

Pusat Pemakanan dan Diabetik Kardiovaskular

Institut Penyelidikan Perubatan,Jalan Raja Muda Abdul Aziz

50300 Kuala Lumpur, Malaysia

Osman Ali

Sekolah Perubatan, Universiti Malaysia Sabah

88999 Kota Kinabalu, Sabah, Malaysia

Diserahkan: 21 Mei 2008 / Diterima: 11 November 2008

ABSTRAK

Selenium memainkan peranan penting dalam mengekalkan status kesihatan manusia. Pengambilan selenium yang tidak mencukupi boleh menjadi penyebab kepada kejadian penyakit. Satu kajian hirisan lintang telah dijalankan untuk menilai paras selenium serum dalam kalangan populasi di Daerah Hulu Langat, Selangor, Malaysia. Seterusnya taburan menurut faktor sosiodemografi dikenal pasti. Populasi di Daerah Hulu Langat dipilih secara persampelan rawak yang melibatkan enam mukim iaitu Ulu Langat, Ampang, Kajang, Cheras, Beranang dan Semenyih. Seramai 415 orang subjek berumur antara 5-64 tahun telah mengambil bahagian dalam kajian ini. Sampel darah diambil untuk melihat paras selenium dalam serum. Hasil mendapati paras selenium keseluruhan subjek ialah 1.67 + 0.44 µmol/l. Hasil ujian ANOVA dua hala mendapati tiada perbezaan paras selenium yang bererti menurut jantina dengan nilai p=0.981 (p>0.05). Manakala terdapat perbezaan paras selenium yang bererti menurut kumpulan umur dengan nilai p<0.001. Kesan interaksi jantina dan kumpulan umur pula menunjukkan tiada interaksi yang bererti antara kedua faktor tersebut dengan p=0.362 (p>0.05). Perbezaan paras selenium adalah bererti menurut lokasi (p<0.05) bagi kedua-dua jantina. Semakin jauh lokasi dari pusat bandaraya Kuala Lumpur, semakin tinggi paras selenium subjek. Kesimpulannya, paras selenium serum populasi penduduk di Daerah Hulu Langat adalah normal berbanding nilai rujukan dari Makmal Unsur Surih, Institut Robens, University of Surrey iaitu 0.89-1.65 µmol/l untuk dewasa.

Kata kunci: Daerah Hulu Langat; paras normal; Selangor; selenium; serum 

ABSTRACT

Selenium plays an important role in maintaining human health status. Insufficient intake of selenium could lead to disease development. One cross-sectional study was conducted to assess serum selenium levels among populations of Hulu Langat District, Selangor, Malaysia. Furthermore, its pattern according to the socio demographic factors of the subjects was identified. The populations of Hulu Langat District involving six sub-districts namely Ulu Langat, Ampang, Kajang, Cheras, Beranang and Semenyih were randomly selected. A total of 415 subjects aged between 5-64 years old were involved in the study. Blood sample was taken to assess serum selenium levels. Results showed that overall selenium levels were 1.67 + 0.44 µmol/l. The result of Two Way ANOVA showed no significant difference of selenium levels according to gender with the value p=0.981 (p>0.05). Whilst there was significant difference of selenium levels according to age groups with the value p<0.001. Interaction effect for gender and age group showed no significant effect with the value p=0.362(>0.05). Selenium levels are significantly different according to location (p<0.05) for both gender. Selenium levels were higher for subject who live further from city centre of Kuala Lumpur. In conclusion, the population of Hulu Langat District selenium levels were normal if compared to reference value from Trace Element Lab, Robens Institute, University of Surrey i.e. 0.89-1.65 µmol/l for adult.

Keyword: Hulu Langat district; normal level; selenium; Selangor; serum 

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*Pengarang untuk surat-menyurat; email: ismarul@medic.ukm.my