PCOS RESEARCH TEAM

About

Polycystic Ovarian Syndrome (PCOS) Research team is a subunit of the Reproductive Research Team. It is established to provide platforms for healthcare research and ultimately aim to build anevidence-based approach in the management of PCOS patients at our center. Currently, our team is conducting researches on molecular aspects related to endometrial receptivity and oocytesquality among PCOS patients undergoing IVF. In this project, we are collaborating with other faculty and expertise ie. physiology, and UKM Medical Molecular Biology Institute (UMBI) in order to achieve powerful and relevant results. We hope that this will aspire more researchers to participate and contribute to society.

Research Unit Members

Profesor Madya Dr. Muhammad Azrai Abu

Profesor Madya Dr. Abdul Kadir Abdul Karim

Profesor Madya Dr. Mohd Faizal Ahmad

Dr. Nor Haslinda Abd Aziz

Selected Research Projects

1. Endometrial heparin-binding epidermal growth factor expression in implantation window of obese women with Polycystic Ovarian Syndrome(PCOS) (FRGS)
2. Investigating the Expression of Endometrial Receptivity Markers in Women with Polycystic Ovarian Syndrome (PCOS) following Progesterone Therapy (Geran Fakulti) 
3. Elucidating The Gene Expression Of Grem1 In Cumulus Cells And Its Association With HOMA-IR Among PCOS Women (Geran Fakulti)
4. Association of nutritional status, dietary pattern, environmental contaminants, physical activity and stress in relation to infertility in infertile Malaysian reproductive aged women (Geran Kebangsaan)

Selected Research Publications

1. A systematic review and integrated bioinformatic analysis of candidate genes and        pathways in the endometrium of patients with polycystic ovary syndrome during the implantation window. Frontier in Endocrinology, jilid 13, halaman 1-10. https://doi.org/10.3389/fendo.2022.900767
2. Sex steroid receptors in polycystic ovary syndrome and endometriosis: Insights from    laboratory studies to clinical trials. Biomedicines, jilid 10, halaman 1-21. https://doi.org/10.3390/biomedicines10071705
3. Endometrial heparin-binding epidermal growth factor gene expression and hormone   level changes in implantation window of obese women with polycystic ovarian syndrome
   Biomedicines, jilid 11, halaman 1 – 9. https://doi.org/10.3390/biomedicines11020276
4. PCOS and role of cumulus gene expression in assessing oocytes quality. Frontier in Endocrinology 2022, jilid 13, nombor 843867. https://doi.org/10.3389/fendo.2022.843867
5. The reliability and validity of the Malay version of Polycystic Ovarian Syndrome health-related quality of life questionnaire. Frontier of Endocrinology 2022, jilid 13, nombor 848860. https://doi.org/10.3389/fendo.2022.848860.
6. Endometrial avB3 Integrin expression in obese women with polycystic ovarian syndrome       (PCOS) following progesterone therapy. Medical Journal of Malaysia 2023