Malaysian
Journal of Analytical Sciences Vol 20 No 4 (2016): 844 - 848
DOI:
http://dx.doi.org/10.17576/mjas-2016-2004-18
ISOLATIOn OF Flavonols from the stems of Malaysian
Uncaria cordata var. ferruginea (Blume) Ridsd.
(Pemisahan Flavonol dari batang Uncaria cordata
var. ferruginea (Blume) Ridsd. Malaysia)
Nur Hakimah Abdullah1, Fatimah Salim2,3,
Rohaya Ahmad1,2*
1Faculty of Applied Science,
Universiti
Teknologi MARA, 40450, Shah Alam, Selangor, Malaysia
2Atta– ur– Rahman Institute for
Natural Products Discovery,
Universiti Teknologi MARA Kampus Puncak
Alam, 42300 Bandar Puncak Alam, Selangor, Malaysia
3Center of
Foundation Studies,
Universiti Teknologi MARA, Dengkil Campus,
43800 Dengkil, Selangor, Malaysia
*Corresponding author: rohayaahmad@salam.uitm.edu.my
Received:
24 February 2015; Accepted: 27 October 2015
Abstract
Continuing our interest in the genus, a phytochemical investigation on Uncaria
cordata var. ferruginea collected
from Hutan Pasir Raja, Malaysia has been carried out. Two flavonols
known as quercetin and kaempferol were isolated from the methanolic stem extract of this plant along with other
phenolic compounds and terpenes. The two flavonols are reported for the
first time from this species. The structure of the compounds were elucidated on
the basis of spectroscopic data, mostly 1D-NMR, 2D-NMR as well as comparison
with literature.
Keywords: flavonoid, flavonol,
kaempferol, quercetin, Uncaria cordata
Abstrak
Dalam meneruskan minat kami terhadap genus ini, satu kajian fitokimia ke
atas Uncaria cordata var. ferruginea
yang diambil dari Hutan Pasir Raja, Malaysia telah dijalankan. Dua
flavonol dikenali sebagai quercetin dan kaempferol telah diasingkan daripada
ekstrak metanol bahagian batang tumbuhan ini bersama sebatian fenolik lain dan
terpena. Kedua-dua flavonol ini dilaporkan buat pertama kali daripada spesies
ini. Struktur sebatian telah dielusidasi berdasarkan data spektroskopi,
terutamanya 1D-NMR, 2D-NMR dan juga perbandingan dengan kajian
literatur.
Kata kunci: flavonoid, flavonol,
kaempferol, quercetin, Uncaria cordata
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