Sains Malaysiana 34(2):  77-80 (2005)

Injectable Hydroxyapatite - b-Tricalcium Phosphate

 – Calcium Sulphate Biocement

(Biosimen Hidroksiapatit-b-Trikalsium Fosfat – Kalsium Sulfat Boleh Suntik)

Wan Khartini Wan Khodir, Roslinda Shamsudin, Abdul Razak Daud

School of Applied Physics, Faculty of Science and Technology

 Universiti Kebangsaan Malaysia

43600 UKM Bangi, Selangor, D.E., Malaysia

Yusof Abdullah

Malaysian Institute for Nuclear Technology Research (MINT) Bangi,

 43000 Kajang, Selangor, D.E. Malaysia

ABSTRACT

Injectable biocement as bone substitute material for filling in parts of defect bone and capable of setting itself in the body was produced based on a mixture of 40-50% hydroxyapatite, 10-20% b-tricalcium phosphate and 40-60% calcium sulphate dehydrate.  Two different liquids were used for the preparation of the biocements, namely deionised water and phosphate buffer solution (pH 7).  The influences of powder composition, weight ratio of liquid-to-powder and powder particle size on the injectability; setting time and compressive strength of the cement were reported.

Keywords:  Hydroxyapatite; injectability, Compresvice strength

ABSTRAK

Biosimen boleh suntik sebagai bahan pengganti tulang untuk mengisi ruang pada tulang yang cacat dan boleh mengeras sendiri dalam badan telah dihasilkan berasaskan campuran hidroksiapatit (40-50%). b-trikalsium fosfat (10-20%) dan kalsium sulfat dihidrat (40-60%).  Dua jenis cecair telah digunakan bagi penyediaan biosemen iaitu air nyahion dan larutan penimbal fosfat (pH 7). Pengaruh komposisi serbuk, nisbah berat cecair terhadap berat serbuk dan saiz zarah serbuk terhadap kebolehsuntikan, masa pengerasan dan kekuatan mampatan simen dilaporkan.

Kata kunci: Hidroksiapatit, kebolehsuntikan, kekuatan mampatan.

RUJUKAN/REFERENCES

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