Sains Malaysiana 42(1)(2013): 59–63

 

Saliva and Dental Caries in Down Syndrome Children

(Air Liur dan Karies Pergigian dalam Kalangan Kanak-kanak Sindrom Down)

 

 

A.R. Normastura*, Z. Norhayani & Y. Azizah

School of Dental Sciences, Health Campus, Universiti Sains Malaysia

16150, Kubang Kerian, Kelantan, Malaysia

 

M.D. Mohd Khairi

Department of Otorhinolaryngology, School of Medical Sciences, Health Campus

Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia

 

Diserahkan: 30 November 2011/Diterima: 24 Mei 2012

 

ABSTRACT

The objective of this study was to determine the association between dental caries and salivary characteristics (flow rate and pH) in the children with Down syndrome. A cross sectional study was conducted on 53 Down syndrome children at selected Down syndrome centres in Kelantan. Sociodemographic data was obtained, resting flow rate and pH were measured using Saliva-Check BUFFER® by GC co., Japan and clinical oral examination was done. Caries experience was calculated based on the index of decayed, missing and filled teeth (DMFT) for permanent dentition and decayed and filled (dft) for deciduous dentition. The mean age of the children was 11.7 (SD 5.51) years and 98.1% of them were Malays. The prevalence of dental caries for deciduous and permanent dentition was 57% (95% CI: 43%-70%) and 74% (95% CI: 61%-86%), respectively. The mean dft was 4.2 (SD 5.66) and DMFT was 4.7 (SD 4.97). The mean resting flow rate was 0.19 (SD 0.10) mL/min while mean pH was 6.2 (SD 0.45). There were no significant differences in the saliva resting flow rate and pH between the low and high carious group in both the deciduous and permanent dentitions (p>0.05). Caries prevalence was low in the deciduous but higher in permanent dentition in children with Down syndrome. Saliva resting flow rate and pH did not influence the caries experience.

 

Keywords: Caries; saliva flow rate; salivary pH; Trisomy 21

 

ABSTRAK

Objektif kajian ini adalah untuk menentukan kaitan antara karies pergigian dengan ciri-ciri air liur (kadar aliran dan pH) dalam kalangan kanak-kanak Sindrom Down. Kajian hirisan lintang ini telah dilakukan ke atas 53 kanak-kanak Sindrom Down di beberapa pusat Sindrom Down di Kelantan. Data sosio demografi, kadar aliran air liur dan pH waktu rehat dan pemeriksaan pergigian dilakukan. Kadar pengalaman karies diukur berdasarkan indek karies, kehilangan gigi dan tampalan (DMFT) untuk gigi kekal dan karies dan tampalan (dft) untuk gigi susu. Purata umur kanak-kanak terlibat ialah 11.7 (SD 5.51) dan 98.1% daripada mereka adalah Melayu. Prevalen karies gigi untuk gigi susu dan kekal ialah 57% (95% CI: 43%-70%) dan 74% (95% CI: 61%-86%). Purata dft ialah 4.2 (SD 5.66) dan DMFT ialah 4.7 (SD 4.97). Purata kadar air liur ialah 0.19 (SD 0.10) mL/min manakala pH ialah 6.2 (SD 0.45). Tiada perbezaan yang signifikan dalam kadar aliran air liur waktu rehat dan pH dalam kedua-dua kumpulan berkaries rendah dan tinggi (p>0.05) pada gigi susu dan kekal. Prevalen karies gigi susu adalah lebih rendah berbanding dengan gigi kekal. Kadar aliran air liur dan pH tidak menentukan pengalaman karies.

 

Kata kunci: Kadar aliran air liur; karies pergigian; pH air liur; Trisomi 21

 

RUJUKAN

Creighton, W.E. & Wells, H.B. 1966. Dental caries experience in institutionalized mongoloid and nonmongoloid children in North Carolina and Oregon. Journal of Dental Research 45(1): 66-75.

de Castilho, A.R.F., Pardi, V. & Pereira, C.V. 2007. Caries prevalence, level of mutans streptococci, salivary flow rate and buffering capacity in subjects with Down syndrome. Brazilian Journal of Oral Sciences 6(21): 1331-1336.

Desai, S.S. 1997. Down syndrome: A review of the literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 84(3): 279-285.

Farsi, N.M.A. 2007. Signs of oral dryness in relation to salivary flow rate, pH, buffering capacity and dry mouth complaints. BMC Oral Health: 1-6. doi: 10.1186/1472-6831-7-15.

Hennequin, M., Faulks, D., Veyrune, J-L. & Bourdiol, P. 1999. Significance of oral health in persons with Down syndrome: A literature review. Developmental Medicine and Child Neurology 41(4): 275-283.

Hoe, T.S., Boo, N.Y. & Clyde, M.M. 1989. Incidence of Down’s syndrome in a large Malaysian maternity hospital over an 18 months period. Singapore Medical Journal 30: 246-248.

Kirstila, V., Hakkinen, P., Jentsch, H., Vilja, P. & Tenovuo, J. 1998. Longitudinal analysis of the association of human salivary antimicrobial agents with caries increment and cariogenic microorganisms: A two-year cohort study. Journal of Dental Research 77(1): 73-80.

Klein, H., Palmer, C. & Knutson, J. 1938. Studies on dental caries: Dental status and dental needs of elementary school children. Public Health Reports (Washington, D. C.:1974) 53: 751-765.

Lamkin, M.S. & Oppenheim, F.G. 1993. Structural features of salivary function. Critical Reviews in Oral Biology and Medicine 4(3-4): 251-259.

Mason, J. 2004. Oral disease patterns in the United States. In Concepts in Dental Public Health. USA: Lippincott Williams and Wilkins. p. 207.

Morinushi, T., Lopatin, D.E. & Tanaka, H. 1995. The relationship between dental caries in the primary dentition and anti S. mutans serum antibodies in children with Down’s syndrome. The Journal of Clinical Pediatric Dentistry 19(4): 279-284.

National Institute of Dental and Craniofacial Research, National Institutes of Health, US Department of Health and Human Services. 2008. Practical Oral Care for People with Down Syndrome. Assessed March 20, 2009. http://www.nidcr.nih.gov/NR/rdonlyres/A93F980E-A9A9-4C84-B904-2D26C99093CC/0/DownSyndrome.pdf.

Nunn, J.H., Gordon, P.H. & Carmichael, C.L. 1993. Dental disease and current treatment needs in a group of physically handicapped children. Community Dental Health 10(4): 389-396.

Oral Health Division, Ministry of Health Malaysia. 1998. National Oral Health Survey of School Children 1997 (NOHSS’97). MOH/K/GIG/ 6.98 (RR).

Oral Health Division, Ministry of Health Malaysia. 2004. Oral Healthcare for Children with Special Needs. Guidelines for Implementation. MOH/K/GIG/7.2004 (GU): p 1.

Oral Health Division, Ministry of Health Malaysia. 2005. Oral Healthcare in Malaysia. MOH/K/GIG/4.05 (BK).

Oral Health Division, Ministry of Health Malaysia. 2007. The National Oral Health Survey of Preschool Children 2005 (NOHPS 2005): Oral Health Status and Treatment Needs.

Oredugba, F.A. 2007. Oral health condition and treatment needs of a group of Nigerian individuals with Down syndrome. Down Syndrome Research and Practice 12(1): 72-77.

Pilcher, E.S. 1998. Dental care for the patient with Down syndrome. Journal Down Syndrome Research and Practice 5(3): 111-116.

Siquiera, W.L., Bermejo, P.R., Mustacchi, Z. & Nicolau, J. 2005. Buffer capacity, pH and flow rate in saliva of children aged 2-60 months with Down syndrome. Clinical Oral Investigations 9: 26-29.

Stabholz, A., Mann, J., Sela, M., Schurr, D., Steinberg, D., Dori, S. & Shapira, J. 1991. Caries experience, periodontal treatment needs, salivary pH, and Streptococcus mutans counts in a preadolescent Down syndrome population. Special Care in Dentistry 11(5): 203-208.

Wilkins, E.M. 1999. The patient with mental retardation. In: Clinical Practices of the Dental Hygienist. 8th Ed. USA: Lippincott Williams & Wilkins. pp. 814-815.

Yarat, A., Akyuz, S., Koc, L., Erdem, H. & Emekli, N. 1999. Salivary sialic acid, protein, salivary flow rate, pH, buffering capacity and caries indices in subjects with Down’s syndrome. Journal of Dentistry 27(2): 115-118.

 

*Pengarang untuk surat-menyurat; email: normastura@kck.usm.my

 

 

 

 

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