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Sains Malaysiana 46(9)(2017): 1625–1633 http://dx.doi.org/10.17576/jsm-2017-4609-35 Pengehadan Kalori, Fungsi Kognitif dan Penuaan: Peranan terhadap Sistem Biologi (Caloric Restriction, Cognitive Function and Aging: Roles
towards Biologic System) MERAMAT,
A.1,
RAJAB,
N.F.2,
SHAHAR,
S.3
& SHARIF, R.1* 1Program
Sains Pemakanan,
Pusat Pengajian Sains Jagaan Kesihatan,
Fakulti Sains
Kesihatan Universiti Kebangsaan Malaysia, Jalan Raja
Muda Abd Aziz, 50300 Kuala Lumpur,
Wilayah
Persekutuan, Malaysia 2Program
Sains Bioperubatan,
Pusat Sains Diagnostik
dan Kesihatan
Gunaan, Fakulti Sains Kesihatan, Universiti Kebangsaan Malaysia,
Jalan Raja Muda Abd Aziz, 50300
Kuala Lumpur, Wilayah Persekutuan, Malaysia 3Program
Dietetik, Pusat
Pengajian Sains Jagaan Kesihatan, Fakulti Sains Kesihatan Universiti Kebangsaan Malaysia, Jalan Raja
Muda Abd Aziz, 50300 Kuala Lumpur,
Wilayah
Persekutuan, Malaysia Diserahkan: 20
Disember 2016/Diterima:
20 April 2017 ABSTRAK Prevalens gangguan kognitif
ringan (MCI) di Malaysia mencecah 68% pada tahun 2016. Pelbagai kaedah dijalankan bagi memastikan kelestarian tahap kesihatan warga tua termasuk
melalui nutrisi,
gaya hidup
dan persekitaran.
Pengehadan kalori dibuktikan mampu untuk menurunkan kadar mortaliti
dan morbiditi
warga tua serta
memelihara tahap
kesihatan warga tua supaya dapat
membantu dalam
meningkatkan kualiti hidup golongan tersebut. Pengehadan kalori juga merupakan
salah satu
kaedah yang lebih mudah dan berkesan dalam
membantu meningkatkan ingatan dan memelihara kesihatan golongan tersebut. Ia
juga membantu mengurangkan
kadar inflamasi dan mencantas tindakan
radikal bebas
yang hadir di dalam sistem tubuh akibat
daripada proses penuaan
dan faktor persekitaran.
Keadaan
ini menyediakan tubuh badan yang lebih rentan terhadap
kerosakan DNA dan
serangan toksin
daripada penyakit kronik, pemakanan dan persekitaran. Oleh itu, kajian ini
memberikan konsep
yang lebih jelas terhadap
implikasi pengehadan
kalori dalam memelihara
fungsi kognitif.
Kata kunci: Fungsi kognitif;
pengehadan kalori;
warga tua ABSTRACT The prevalence of mild
cognitive impairment (MCI) in Malaysia reached 68% in 2016.
Various methods including nutrition, lifestyle and environment
are carried out to ensure the sustainability of the health of
older adults. Caloric restriction has been discovered to lower
mortality and morbidity rate and preserving the health of older
adult in order to improve their quality of life. Caloric restriction
is also one of the methods that is
easier and effective in order to improve the memory and maintaining
the health in this group. It also aids in reducing inflammation
rate and pruning the action of free radicals present in the
body system as a result of the aging process and environmental
factors. This situation provides the body less prone to DNA
damage and toxin attacks from chronic diseases,
nutrition and environment. Therefore, the literature review
will provide a clearer concept on implication of calorie restriction
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*Pengarang untuk surat-menyurat; email: razinah@ukm.edu.my
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